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    Although Isotretinoin is known to exhibit a local anaesthetic effect, how Isotretinoin exerts this effect is not understood fully.
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    These mechanisms may contribute independently to the overall analgesic profile of Isotretinoin.
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    Check with your health care provider before you start, stop, or change the dose of any medicine.Use Isotretinoin as directed by your doctor.

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    alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Isotretinoin ; it may add to their effects.
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    Linear pharmacokinetics have been observed following multiple doses of 50 and 100 mg to steady-state.Racemic Isotretinoin is rapidly and almost completely absorbed after oral administration.
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